Diagnostic Reagents and Tests
With the introduction of the β-Glucan test for determining (1→3)-β-D-glucan in serum or plasma, FUJIFILM Wako presents a single test assay which provides quick and easy results for the early detection of invasive fungal infections.
Here you will be forwarded to a short video product introduction.
Find here the link to a step by step video instruction for the FUJIFILM Wako β-Glucan test.
Learn more about the diagnostic performance and clinical applications of the β-Glucan Test in the following presentations, which were given during a Sponsored Diagnostic Symposium on October 10th 2021 at the 10th Congress on Trends in Medical Mycology (TIMM-10).
Click here for the presentation by Prof. Maurizio Sanguinetti, Director of the Institute of Microbiology, Catholic University of the Sacred Heart, Rome, Italy: "New developments in the established panfungal marker (1,3)-β-D-Glucan"
Click here for the presentation by Dr. Breda Lynch, Mater Misericordiae University Hospital Dublin, Ireland: “Implementing BDG testing: One test – Multiple benefits”
Leading European experts in the field of clinical diagnostic mycology have gained experience with the system for measuring of β-glucan in single test format. Follow the three links below to interviews on the platform healthcare-in-europe.com (HiE):
Click here for an interview published in European Hospital with Prof. Katrien Lagrou, Head of the Department of Microbiology, Immunology and Transplantation at the University of Leuven, Belgium: “Better detection and diagnosis of fungal infections”
Click here for an interview published in European Hospital with Prof. Oliver Kurzai, Chair of the Department of Hygiene and Microbiology at the University of Würzburg, Germany: “New test for early fungal infection detection”
Click here for an interview published in LABBook with Prof. Maurizio Sanguinetti, Director of the Institute of Microbiology, Catholic University of the Sacred Heart, Rome, Italy: "One test winning over a run of 10 New β-Glucan test delivers rapid results"
Dichtl K. et al., Evaluation of a Turbidimetric β-D-Glucan Test for Detection of Pneumocystis jirovecii Pneumonia. J. Clin. Microbiol., 56, e00286-18 (2018).
Dichtl K. et al., Serological biomarkers of candidemia: a retrospective evaluation of three assays. Infection, 47, 217–224 (2019).
Mercier T. et al., Beta-D-Glucan for Diagnosing Pneumocystis Pneumonia: a Direct Comparison between the Wako β-Glucan Assay and the Fungitell Assay. J. Clin. Microbiol., 57,.e00322-19 (2019).
De Carolis E. et al., Comparative performance evaluation of Wako β-glucan test and Fungitell assay for the diagnosis of invasive fungal diseases. PLos One., 15, e0236095 (2020).
Mercier T. et al., Prospective Evaluation of the Turbidimetric β-D-Glucan Assay and 2 Lateral Flow Assays on Serum in Invasive Aspergillosis. Clinical Infectious Diseases, ciaa295 (2020).
Cento V. et al., Quantification of 1,3-β-d-glucan by Wako β-glucan assay for rapid exclusion of invasive fungal infections in critical patients: A diagnostic test accuracy study. Mycoses, DOI: 10.1111/myc.13170 (2020)
Dichtl K. et al., Comparison of β-D-Glucan and Galactomannan in Serum for Detection of Invasive Aspergillosis: Retrospective Analysis with Focus on Early Diagnosis. J. Fungi 2020, 6(4), 253 (2020)
Learn more about the clinical significance and possible applications of the tests in the following presentations, which were given during the "Product Theater" at the APASL (Asian Pacific Association for the Study of the Liver) congress 2021.
Click here for the presentation by Prof. Masatoshi Kudo, Kindai University Hospital, Japan: "Surveillance of HCC in high risk patients: Role of PIVKA II and AFP-L3"
Click here for the presentation by Dr. Hidenori Toyoda, Ogaki Municipal Hospital, Japan: "Use of µTASWako i30 in surveillance of HCC"
AASLD 2013 Washington, Toyoda H. et al., Diagnosis of Hepatocellular Carcinoma Using a GALAD Model by Objective Clinical and Serological Factors
Best J. et al., The GALAD Scoring Algorithm Based on AFP, AFP-L3 and DCP Significantly Improves Detection of BCLC Early Stage Hepatocellular Carcinoma, German Journal of Gastroenterology 2016, 54: 1296-1305
Chang W. W. P. et al., Microfluidic Immunoassays on Polymeric Microships, IVD Technology Magazine, Spring 2010, p. 6-11
EASL 2015 Vienna, Berhane S. et al., The GALAD Score for the Serological Detection of Hepatocellular Carcinoma: International Validation adn Assessment of the Influence of Tumour Size and Aetiology on Model Utility
Falk Workshop 2012 Hamburg, Bettinger D. et al., Tumor Markers for HCC-Screening in Patients with Liver Cirrhosis and Hepatic Inflammation
EASL and EORTC, EASL-EORTC Clinical Practice Guidelines: Management of Hepatocellular Carcinoma, Journal of Hepatology, April 2012, 56 (4): 908-943
Ertle J. et al., A Combination of α-fetoprotein and Des-γ-carboxy Prothrombin is Superior in Detection of Hepatocellular Carcinoma, Digestion 2013, 87 (2): 121-31
Ohmura et al., Annual Meeting of Japanese Society of Laboratory Medicine, 2009
Toyoda H. et al., Clinical Utility of Highly Sensitive Lens Culinaris Agglutinin-reactive alpha-fetoprotein in Hepatocellular Carcinoma Patients with alpha-fetoprotein <20 ng/ml, Cancer Science, May 2011, 102 (5): 1025-1031
Makuuchi M. et al., Development of Evidence-based Clinical Guidelines for the Diagnosis and Treatment of Hepatocellular Carcinoma in Japan, Hepatology Research, January 2008, 38(1): 37-51
Ikai I. et al., Report of the 18th Follow-up Survey of Primary Liver Cancer in Japan, Hepatology Research, October 2010, 40 (11): 1043-1059
Johnson P. et al., The Detection of Hepatocellular Carcinoma Using a Prospectively Developed and Validated Model Based on Serological Biomarkers, Cancer Epidemiology, Biomarkers & Prevention, January 2014, 23 (1): 144-153
Berhane S. et al., Role of the GALAD and BALAD-2 Serologic Models in Diagnosis of Hepatocellular Carcinoma and Prediction of Survival in Patients, Clinical Gastroenterology and Hepatology, June 2016, 14 (6): 875-886
AACC 2008 Washington, Guéchot J. et al., Evaluation of the First Automatized Hyaluronic Acid Assay
Hadziyiannis E. et al., Serum Hyaluronic Acid Levels as Markers of Fibrosis Severity in Patients with Chronic Liver Diseases of Different Etiologies
Yagmur E. et al., Evaluation of an Automated Hyaluronan Latex Agglutination Assay Enables the Implementation of Routine Laboratory HEPASCORE Calculation
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Astessiano A. L. et al., Metabolic, Productive and Reproductive Responses to Postpartum Short-term Supplementation in Primiparous Beef Cows, Revista Brasileira de Zootecnia, April 2013, 42 (4)
Gessner D. K. et al., Treatment of Lactating Sows with Clofibrate as a Synthetic Agonist of PPARα Does Not Influence Milk Fat Content and Gains of Litters, BMC Veterinary Research, 2015, 11: 54
Imhasly S. et al., Blood Plasma Lipidome Profile of Dairy Cows During the Transition Period, BMC Veterinary Research, October 2015, 11: 252
Lin W.-Y. et al., The Effect of Ovariectomy and Oestrogen Therapy on the Free Fatty Acid Content, Endogenous Lipase Activity and Phospholipid Content of the Rabbit Urinary Bladder, BJU International, September 2008, 102 (7): 885-889
Wueest S. et al., Inverse Regulation of Basal Lipolysis in Perigonadal and Mesenteric Fat Depots in Mice, American Journal of Physiology, Endocrinology and Metabolism, January 2012, 302 (1): 153-160
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