µTASWako™ AFP-L3 Test
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µTASWako™ AFP-L3 Test is an in vitro diagnostic blood test for the risk assessment of developing Hepatocellular Carcinoma (HCC).
AFP-L3 is an isoform of the glycoprotein alpha-fetoprotein (AFP). It has an additional α 1-6 fucose residue attached at the reducing end of N-acetylglucosamine. Using affinity electrophoresis with the lectin Lens culinaris agglutinin (LCA), AFP can be fractionated into the three variants L1, L2 and L3. AFP-L1 with the lowest affinity for LCA is the most prevalent fraction in patients with non-malignant liver diseases like chronic hepatitis or liver cirrhosis.
µTASWako™ AFP-L3 Test measures the ratio of AFP-L3 to total AFP as percentage and allows an early diagnosis of HCC. This test is run on the µTASWako™ i30 device.
All test components are CE-certified according to Directive 98/79/EC on in vitro diagnostic medical devices.
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