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May 2014
Objective biomarker-based models for improved detection and prognosis assessment of HCC

Recently, researchers from the University of Birmingham and the University of Liverpool in the United Kingdom, under the direction of Prof. Philip Johnson, published data on the GALAD model for hepatocellular carcinoma (HCC) risk determination and the BALAD-2 model for prognosis assessment. The biomarkers AFP, AFP-L3 and DCP are key components in both models.

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February 2014
Launch of HCC biomarkers AFP-L3 and DCP in Romania by Proton Impex 2000 S.r.l.
Proton Impex 2000 S.r.l. and Wako Chemicals GmbH signed an agreement for the distribution of the hepatocellular carcinoma (HCC) biomarkers AFP-L3 and DCP, as well as the microchip-based platform µTASWakoTM i30. The reference laboratory Lotus Medical in Bucharest will be the first laboratory to offer the biomarkers.

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February 2014
Lansarea biomarkerilor HCC AFP - L3 și DCP în România de către Proton Impex 2000 SRL
Proton Impex 2000 SRL şi Wako Chemicals GmbH au semnat un acord de distribuţie al biomarkerilor
HCC AFP - L3 şi DCP , prin intermediul platformei de ultima generatie μTASWakoTM i30.  Laboratorul
Lansarea biomarkerilor HCC AFP - L3 şi DCP în România de către Proton Impex 2000 SRL clinic Lotus Medical din Bucureşti este primul utilizator din Romania al acestui sistem performant.

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January 2014
HCC biomarkers AFP-L3 and DCP are now available at the University Hospital of Essen, Germany

The University Hospital of Essen signed an agreement with Wako Chemicals GmbH to provide the serum tests AFP-L3 and DCP in the central laboratory under the management of Dr. med. L. Volbracht. These innovative tests are now available for the Department of Gastroenterology and Hepatology, University Hospital of Essen, directed by Prof. Dr. med. G. Gerken to aid in the diagnosis of hepatocellular carcinoma (HCC).

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March 2013
Combination of biomarkers AFP and DCP is superior to AFP alone in detection of HCC
Prof. Schlaak and clinicians from the University Hospital Essen, Germany, demonstrate that the combined use of the serological biomarkers AFP and DCP could improve early detection of HCC.

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January 2013
Automated HA LT enables implementation of routine Hepascore calculation
Dr. Yagmur, Medical Care Centre Dr. Stein and colleagues, Moenchengladbach, and study partners of the University Hospital Aachen, Germany, presented results on the analytical evaluation of HA LT during the GASL congress 2013. How this enables the implementation of an automated Hepascore has been discussed.

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December 2012
Publication on AFP-L3% and DCP levels in cases with misleading AFP results from Greece

Clinicians of the Hippokration General Hospital in Athens, Greece, published data on the diagnostic performance of AFP-L3% and DCP in HCC patients with non-diagnostic AFP levels and non-HCC patients with elevated AFP levels.

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November 2012
Study results on serum hyaluronic acid (HA) presented during the annual meeting 2012 of the American Association for the Study of Liver Diseases (AASLD)
Prof. G. Papatheodoridis and other researchers from the Hippokration General Hospital and the Laboratory of Histology & Embryology of the University of Athens, Greece, presented study results on the liver fibrosis marker HA by two posters.

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October 2012
Towards the serological diagnosis of HCC – study data on HCC biomarkers presented at the ILCA congress by the University of Birmingham, UK

At the annual congress of the International Liver Cancer Association (ILCA) in Berlin in September 2012, researchers of the Department of Cancer Science from the University of Birmingham, UK, directed by Prof. P. Johnson, showed prospective study data on AFP, AFP-L3 and DCP in discovery and validation patient cohorts.

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March 2012
Hyaluronic Acid alone or included in Hepascore reveals good ability to detect all stages of chronic liver disease

Dr. E. G. M. Lazarova from the hospital Erasme in Brussels, Belgium published results of a prospective analysis regarding the automated quantification of serum hyaluronic acid (HA) for non-invasive assessment of liver fibrosis in chronic hepatic diseases.

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January 2012
Study data on HCC biomarkers presented at Falk Workshop and GASL congress 2012 in Hamburg, Germany
At the Falk Workshop and the subsequent annual congress of the German Association for the Study of the Liver (GASL) in January 2012 in Hamburg, researchers from the University Hospitals Essen and Freiburg presented current study results about the HCC biomarkers AFP-L3% und DCP.

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